Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium.

Development of methodology to support molecular endotype discovery from synovial fluid of individuals with knee osteoarthritis: The STEpUP OA consortium.

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<h4>Objectives</h4>To develop a protocol for largescale analysis of synovial fluid proteins, for the identification of biological networks associated with subtypes of osteoarthritis.<h4>Methods</h4>Synovial Fluid To detect molecular Endotypes by Unbiased Proteomics in Osteoar...

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Main Authors: Yun Deng, Thomas A Perry, Philippa Hulley, Rose A Maciewicz, Joanna Mitchelmore, Darryl Perry, Staffan Larsson, Sophie Brachat, André Struglics, C Thomas Appleton, Stefan Kluzek, Nigel K Arden, David Felson, Brian Marsden, Brian D M Tom, Laura Bondi, Mohit Kapoor, Vicky Batchelor, Jennifer Mackay-Alderson, Vinod Kumar, L Stefan Lohmander, Tim J Welting, David A Walsh, Ana M Valdes, STEpUP OA Consortium, Tonia L Vincent, Fiona E Watt, Luke Jostins-Dean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0309677
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https://doi.org/10.1371/journal.pone.0309677

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