Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model

Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model

Abstract Administration of pulmonary surfactant is crucial for the treatment of respiratory distress syndrome (RDS) in preterm infants. The aim of this study is to evaluate the potential of Curosurf atomization via the Endosurf device, a recently developed spray technology, as a promising approach f...

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Main Authors: Ghalia Kaouane, Jean-François Berret, Yannick Cremillieux, Noël Pinaud, Fanny Munsch, Bei Zhang, Michael Fayon, Rémy Gérard, Eric Dumas De La Roque, Sophie Perinel-Ragey, Lara Leclerc, Jérémie Pourchez
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Respiratory distress syndrome (ARDS)
Exogenous surfactant
Curosurf
Surfactant atomization
Endosurf medical device
Ex vivo respiratory model
Online Access:https://doi.org/10.1038/s41598-025-03199-x
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https://doi.org/10.1038/s41598-025-03199-x

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