Comparative Gut Proteome of <i>Nyssomyia umbratilis</i> from Leishmaniasis Endemic and Non-Endemic Areas of Amazon Reveals Differences in Microbiota and Proteins Related to Immunity and Gut Function

Comparative Gut Proteome of <i>Nyssomyia umbratilis</i> from Leishmaniasis Endemic and Non-Endemic Areas of Amazon Reveals Differences in Microbiota and Proteins Related to Immunity and Gut Function

The northern region of Brazil is endemic for American Tegumentary Leishmaniasis (ATL) primarily caused by <i>Leishmania guyanensis</i> and transmitted by the sand fly <i>Nyssomyia umbratilis</i>. The disease occurs at different rates in the municipalities of Manacapuru (MAN)...

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Main Authors: Antonio Jorge Tempone, Guilherme Ian Spelta, Victor Ramos de Almeida, Daniel Machado Giglioti, Erika Moutinho Costa, Izabela Mathias, Helena Vargas, Thais Lemos-Silva, Ana Carolina Pedro dos Santos Ribeiro, Eric Fabrício Marialva, Cláudia Rios-Velasquez, Michel Batista, Marlon Dias Mariano dos Santos, Felipe Arley Costa Pessoa, Yara Maria Traub-Csekö
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
Subjects:
Leishmaniais
<i>Nysomyia umbratilis</i>
<i>Leishmania guyanensis</i>
gut proteomics
microbiota
sand fly and leishmania interaction
Online Access:https://www.mdpi.com/2076-2607/13/6/1304
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