Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupusResearch in context

Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupusResearch in context

Summary: Background: Physical activity is an adjunctive therapy that improves symptoms in people living with systemic lupus erythematosus (SLE), yet the mechanisms underlying this benefit remain unclear. Methods: We carried out a cohort study of 123 patients with SLE enrolled in the California Lupu...

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Main Authors: Sarah L. Patterson, Hoang Van Phan, Chun Jimmie Ye, Cristina Lanata, Sebastián Cruz González, Joonsuk Park, Lindsey A. Criswell, Kamil E. Barbour, Jinoos Yazdany, Maria Dall’Era, Marina Sirota, Patricia Katz, Charles R. Langelier
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:EBioMedicine
Subjects:
Rheumatoid arthritis
Physical activity
Single cell transcriptomics
Lifestyle behaviors
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004687
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