Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice

Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice

Diabetes is prevalent worldwide, but ideally intensive therapeutic strategy in clinical diabetes and diabetic nephropathy (DN) is still lack. Pyruvate is protective from glucometabolic disturbances and kidney dysfunction in various pathogenic insults. Present studies focused on oral pyruvate effects...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xiao Meng Zhang, Hao Deng, Jin Dong Tong, Yi Zhen Wang, Xu Chao Ning, Xiu Hong Yang, Fang Qiang Zhou, Hui Min Jin
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2020/2817972
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Impaired Muscle Regeneration in Ob/ob and Db/db Mice
by: Mai-Huong Nguyen, et al.
Published: (2011-01-01)

Gut Microbiota Composition and Structure of the Ob/Ob and Db/Db Mice
by: Mingsheng Yang, et al.
Published: (2019-01-01)

Investigation of the Protective Effects of Phlorizin on Diabetic Cardiomyopathy in db/db Mice by Quantitative Proteomics
by: Qian Cai, et al.
Published: (2013-01-01)

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in db/db Mice Using Cytokine Antibody Array
by: Xue Mei Fan, et al.
Published: (2018-01-01)

Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice
by: Yun Hu, et al.
Published: (2024-01-01)

Changes in Metabolic Regulation and the Microbiota Composition after Supplementation with Different Fatty Acids in db/db Mice
by: Beatriz Elina Martínez-Carrillo, et al.
Published: (2022-01-01)

Apoptosis in the liver of male <em>db/db</em> mice during the development of obesity and type 2 diabetes
by: S. V. Michurina, et al.
Published: (2020-07-01)

α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach
by: Aimin Cai, et al.
Published: (2025-01-01)

Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice
by: Rui-xi Sun, et al.
Published: (2022-01-01)

Quantifying Podocyte Number in a Small Sample Size of Glomeruli with CUBIC to Evaluate Podocyte Depletion of db/db Mice
by: Jiaoyu Shi, et al.
Published: (2023-01-01)

PPARγ Agonist Rosiglitazone Suppresses Renal mPGES-1/PGE2 Pathway in db/db Mice
by: Ying Sun, et al.
Published: (2013-01-01)

Dynamic Expression of HDAC3 in db/db Mouse RGCs and Its Relationship with Apoptosis and Autophagy
by: Yuhong Fu, et al.
Published: (2020-01-01)

Corrigendum to “Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice”
by: Xiao-Wen Chen, et al.
Published: (2016-01-01)

Impaired Hippocampal Glutamate and Glutamine Metabolism in the db/db Mouse Model of Type 2 Diabetes Mellitus
by: Jens Velde Andersen, et al.
Published: (2017-01-01)

Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse
by: Chunjun Sheng, et al.
Published: (2016-01-01)

Modeling of the Diffusion Bond for SPF/DB Titanium Hollow Structures
by: Xianghai Chai, et al.
Published: (2015-01-01)

Rhein Reduces Fat Weight in db/db Mouse and Prevents Diet-Induced Obesity in C57Bl/6 Mouse through the Inhibition of PPARγ Signaling
by: Yu Zhang, et al.
Published: (2012-01-01)

Enhanced Activity by NKCC1 and Slc26a6 Mediates Acidic pH and Cl− Movement after Cardioplegia-Induced Arrest of db/db Diabetic Heart
by: Minjeong Ji, et al.
Published: (2019-01-01)

FoodMicroDB: A microbiome database for composition and time‐series research in food
by: Yahui Li, et al.
Published: (2024-12-01)

Spatial TinyDB: A Spatial Sensor Database System for the USN Environment
by: Dong-Oh Kim, et al.
Published: (2013-08-01)

SpikeDroidDB: AN INFORMATION SYSTEM FOR ANNOTATION OF MORPHOMETRIC CHARACTERISTICS OF WHEAT SPIKE
by: M. A. Genaev, et al.
Published: (2018-03-01)

Prophage-DB: a comprehensive database to explore diversity, distribution, and ecology of prophages
by: Etan Dieppa-Colón, et al.
Published: (2025-01-01)

Nutrient composition databases in the age of big data: foodDB, a comprehensive, real-time database infrastructure
by: Peter Scarborough, et al.
Published: (2019-06-01)

A 12 dB 0.7 V 𝟖𝟓𝟎𝝁W CMOS LNA for 866 MHz UHF RFID Reader
by: Jie Li, et al.
Published: (2010-01-01)

GutBugDB: a web resource to predict the human gut microbiome-mediated biotransformation of biotic and xenobiotic molecules
by: Usha Longwani, et al.
Published: (2025-01-01)

MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays
by: Alan F. Rubin, et al.
Published: (2025-01-01)

Feasibility and Safely of Oral Rehydration Therapy before Upper Gastrointestinal Endoscopic Submucosal Dissection
by: Yasutoshi Shiratori, et al.
Published: (2020-01-01)

Silicon Nitride Spot-Size Converter with Coupling Loss < 1.5 dB for Both Polarizations at 1W Optical Input
by: Enge Zhang, et al.
Published: (2024-12-01)

Dataset of polarimetric images of mechanically generated water surface waves coupled with surface elevation records by wave gauges linear arrayScienceDB
by: Noam Ginio, et al.
Published: (2025-02-01)

A 10 GHz Dual-Loop PLL With Active Cycle-Jitter Correction Achieving 12dB Spur and 29% Jitter Reduction
by: Yu-Ping Huang, et al.
Published: (2024-01-01)

Associations of Maternal Fructosamine before Delivery in Gestational Diabetes Mellitus Pregnancies with Neonatal Glucometabolic Disorders
by: Zhengxia Mao, et al.
Published: (2022-01-01)

Metabolic and Morphological Aspects of Adaptation of Alkaliphilic Bacillus aequororis 5-DB and Alkali-Tolerant Bacillus subtilis ATCC 6633 to Changes in pH and Mineralization
by: Yuliya Maksimova, et al.
Published: (2024-01-01)

Food Intake and Core Body Temperature of Pups and Adults in a db Mouse Line Deficient in the Long Form of the Leptin Receptor without Misty Mutation
by: Wijang Pralampita Pulong, et al.
Published: (2018-01-01)

Randomized Clinical Trial Comparing The Effect Of Oral Rehydration Therapy With And Without Racecadotril In The Management Of Acute Diarrhea In Children
by: Sughra Zulfiqar, et al.
Published: (2023-12-01)

Pyruvate Kinase Deficiency Causing Priapism
by: Vinay Hanyalu Shankar, et al.
Published: (2023-01-01)

Changes in Texture and Flavor of Dehydrated Shiitake Mushroom during Rehydration
by: LI Qianyu, CAO Xuehui, ZHUO Qiuchen, YOU Kaiyan, LIANG Zhitang, ZHU Danshi
Published: (2025-02-01)

Maternal knowledge, attitude and practice regarding commercial oral rehydration salt solution: experience from a diarrhoeal disease hospital in Bangladesh
by: Tahmeed Ahmed, et al.
Published: (2025-02-01)

Rehydrated corn grain silage with wet brewery residue and different inoculants
by: E. L. L. Lelis, et al.
Published: (2024-06-01)

Impact of processing conditions on the rehydration kinetics and texture profile of freeze-dried carbohydrates sources
by: Vitor Andre Silva Vidal, et al.
Published: (2025-03-01)

Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer’s Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis
by: Shuo Liu, et al.
Published: (2024-01-01)