Structural bioinformatics approaches for predicting novel drug targets in hepatitis C virus proteins: a comprehensive analysis

Abstract This study employs structural bioinformatics approaches to identify and evaluate potential drug targets within the Hepatitis C virus (HCV) proteome. Through integration of homology modeling, molecular docking, and molecular dynamics simulations, we analyzed the structural features and drugg...

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Bibliographic Details
Main Authors: Miao Qu, Mingzhu Gao, Xisheng Sang, Miao Yu, Zihe Guan, Weizhi Chang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12563-w
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