Association study between BGLAP RS1800247-polymorphic variant and type 2 diabetes mellitus development among hypertensive and non-hypertensive Ukrainians

Association study between BGLAP RS1800247-polymorphic variant and type 2 diabetes mellitus development among hypertensive and non-hypertensive Ukrainians

The risk of type 2 diabetes mellitus (T2DM) development depends on a hereditary predisposition. According to the current data, bone tissue enhances insulin gene expression in pancreatic β-cells as well as increases insulin sensitivity of adipocytes, myocytes and hepatocytes through the secretion of...

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Bibliographic Details
Main Authors: Ya. D. Chumachenko, M. O. Kyrychenko, D. M. Ramazanova, M. V. Smiianova, V. Yu. Harbuzova, O. V. Ataman
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2021-06-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
type 2 diabetes mellitus
hypertension
osteocalcin
single nucleotide polymorphism
tt-homozygote
tc-heterozygote
cc-homozygote
Online Access:http://zmj.zsmu.edu.ua/article/view/220651/232308
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http://zmj.zsmu.edu.ua/article/view/220651/232308

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