Around-the-clock noise exposure induces hippocampus apoptosis and subsequent cognitive impairment via the PI3K/SGK1/Foxo3 signaling pathway

Around-the-clock noise exposure induces hippocampus apoptosis and subsequent cognitive impairment via the PI3K/SGK1/Foxo3 signaling pathway

Abstract Background Noise exposure is an environmental stressor associated with cognitive impairment. Workers in specific work environments are often exposed to around-the-clock noise and experience severe emotional and cognitive dysfunctions associated with neuropathology similar to Alzheimer’s dis...

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Bibliographic Details
Main Authors: Yiming Fu, Pengfang Zheng, Xiaojun She, Yingwen Zhu, Bo Fu, Kefeng Ma, Honglian Yang, Xiujie Gao, Bo Cui
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Around-the-clock noise
Apoptosis
Cognitive impairment
Serum/glucocorticoid regulated kinase 1
Online Access:https://doi.org/10.1186/s12967-025-06501-7
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https://doi.org/10.1186/s12967-025-06501-7

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