Insights into immune-related adverse events in colorectal cancer patients receiving neoadjuvant immunotherapy: findings from a multicenter registry study

Insights into immune-related adverse events in colorectal cancer patients receiving neoadjuvant immunotherapy: findings from a multicenter registry study

BackgroundThe growing use of immune checkpoint inhibitors (ICIs) in the neoadjuvant treatment of colorectal cancer (CRC) has highlighted immune-related adverse events (irAEs) as a major concern. This study aimed to investigate the characteristics of irAEs.MethodsThis study was a retrospective, multi...

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Main Authors: Chentong Wang, Quan Wang, Jiaolin Zhou, Aiping Zhou, Xiaojian Wu, Guanyu Yu, Lei Zhou, Yuping Zhu, Weijie Chen, Xiaoyuan Qiu, Liting Sun, Yang Gong, Xiao Zhang, Ganbin Li, Yang An, Han Chen, Xiaoyu Xie, Jinhua Tao, Guole Lin, Hongwei Yao, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint inhibitors
colorectal neoplasms
neoadjuvant therapy
drug toxicities
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529637/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529637/full

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