The role of laminins in cancer pathobiology: a comprehensive review
Abstract Laminins (LMs) are a family of heterotrimeric glycoproteins that form the structural foundation of basement membranes (BM). By acting as molecular bridges between cells and the extracellular matrix (ECM) through integrins and other surface receptors, they regulate key cellular signals that...
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Main Authors: | Elena Nonnast, Emilia Mira, Santos Mañes |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-025-06079-0 |
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