The role of laminins in cancer pathobiology: a comprehensive review

Abstract Laminins (LMs) are a family of heterotrimeric glycoproteins that form the structural foundation of basement membranes (BM). By acting as molecular bridges between cells and the extracellular matrix (ECM) through integrins and other surface receptors, they regulate key cellular signals that...

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Bibliographic Details
Main Authors: Elena Nonnast, Emilia Mira, Santos Mañes
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06079-0
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