EXPERIMENTAL RATIONALE FOR THE USE OF ROPRENE TO PREVENT ISONIAZID-INDUCED LIVER DAMAGES

A model of isoniazid-induced liver damage in fast (females) and slow (males) acetylators was used to study the preventive hepatoprotective effect of the novel drug roprene in doses of 10, 15, and 30 mg/kg as an oil solution. It was found that in terms of a set of biochemical and morphological criter...

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Bibliographic Details
Main Authors: G. N. Mozhokina, N. A. Elistratova, L. P. Mikhailova, O. V. Makarova, V. S. Sultanov, V. B. Trusov
Format: Article
Language:Russian
Published: New Terra Publishing House 2014-07-01
Series:Туберкулез и болезни лёгких
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Online Access:https://www.tibl-journal.com/jour/article/view/104
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