Anti-PD1 based precision induction therapy in unresectable stage III non-small cell lung cancer: a phase II umbrella clinical trial

Anti-PD1 based precision induction therapy in unresectable stage III non-small cell lung cancer: a phase II umbrella clinical trial

Abstract The efficacy and safety of induction-immunotherapy followed by surgery for unresectable Stage III non-small cell lung cancer (NSCLC) remain challenging. In this open-label, single-center, phase II clinical umbrella trial (ChiCTR2000035367), 100 unresectable Stage III NSCLC patients are enro...

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Main Authors: Chengxiang Yi, Dongliang Bian, Jue Wang, Shiqi Hu, Liangdong Sun, Yilv Yan, Suyu Wang, Ziyun Shen, Huansha Yu, Yong Yang, Yirui Zhou, Xiaogang Liu, Nan Song, Yuming Zhu, Deping Zhao, Gening Jiang, Liang Duan, Wenxin He, Dong Xie, Jie Dai, Lele Zhang, Peng Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57184-z
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https://doi.org/10.1038/s41467-025-57184-z

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