Critical contributions of neuronal subtypes to pediatric drug-resistant focal dysplasia

Critical contributions of neuronal subtypes to pediatric drug-resistant focal dysplasia

Approximately 75% of epilepsy cases emerge in childhood, and 10%–30% of these pediatric epilepsy cases are resistant to standard drug therapies; however, the underlying causes of resistance remain poorly understood. Focal cortical dysplasia (FCD) is a primary contributor to pediatric epilepsy and is...

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Main Authors: Yujie Zhang, Lin Li, Fengjun Zhu, Xinyang Zhang, Dan Xia, Qiuling Miao, Cheng Zhong, Shuli Liang, Dezhi Cao, Huafang Zou, Jing Duan, Yousheng Shu, Yi Yao, Jianming Song, Songnian Hu, Jianxiang Liao, Qiang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
focal cortical dysplasia
drug-resistant epilepsy
neuronal subtypes
energy metabolism
fast-spiking neuron
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1566137/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1566137/full

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