Population Pharmacokinetics and Pharmacodynamics of Sitafloxacin in Plasma and Alveolar Epithelial Lining Fluid of Critically Ill Thai Patients With Pneumonia

Population Pharmacokinetics and Pharmacodynamics of Sitafloxacin in Plasma and Alveolar Epithelial Lining Fluid of Critically Ill Thai Patients With Pneumonia

ABSTRACT Sitafloxacin is one of the oral respiratory quinolones for the treatment of community‐acquired pneumonia. The pharmacokinetic (PK) changes of sitafloxacin in critical illness have been previously reported. However, sitafloxacin exposure and target attainment have never been confirmed in thi...

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Main Authors: Taniya Paiboonvong, Preecha Montakantikul, Navarat Panjasawatwong, Noppaket Singkham, Baralee Punyawudho
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Pharmacology Research & Perspectives
Subjects:
alveolar epithelial lining fluid
critically ill patients
Monte Carlo simulations
population pharmacokinetics
Sitafloxacin
Online Access:https://doi.org/10.1002/prp2.70081
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https://doi.org/10.1002/prp2.70081

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