The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management

The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management

Abstract To explore the therapeutic efficacy of L-glutamine (L-Gln) on pathological progression and clinical symptoms of osteoarthritis (OA), and compare with glucosamine sulfate (GS), and celecoxib (CXB). Rats were administered sodium chloride, L-Gln, GS, or CXB via gavage for eight weeks starting...

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Main Authors: Zhongyao Hu, Changming Wang, Chen Wang, Junyan He, Yiqun Yan, Zelin Xu, Yangmang Yu, Ya Yu, Huan Cheng, Lei Liu, Miao Tang, Chun Zhang, Haoran Yu, Juehua Jing, Wendan Cheng
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Osteoarthritis
L-glutamine
Glucosamine sulfate
Celecoxib
Online Access:https://doi.org/10.1038/s41598-025-93357-y
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https://doi.org/10.1038/s41598-025-93357-y

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