Monosodium Urate Crystal Depletion and Bone Erosion Response in Kidney Transplant Recipients With Uncontrolled Gout Treated With Pegloticase: PROTECT Serial Dual-Energy Computed Tomography Findings

Monosodium Urate Crystal Depletion and Bone Erosion Response in Kidney Transplant Recipients With Uncontrolled Gout Treated With Pegloticase: PROTECT Serial Dual-Energy Computed Tomography Findings

Background. Hyperuricemia and gout are associated with poor outcomes in kidney transplant (KT) recipients, including graft failure. The PROspective sTudy of pEglotiCase in Transplant patients (PROTECT) trial showed high urate-lowering efficacy of pegloticase in immunosuppressed KT recipients with un...

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Main Authors: Nicola Dalbeth, MD, Abdul Abdellatif, MD, John K. Botson, MD, Kenneth G. Saag, MD, Ada Kumar, MD, Lissa Padnick-Silver, PhD, Zana Vranic, PhD, Brad A. Marder, MD, Fabio Becce, MD
Format: Article
Language:English
Published: Wolters Kluwer 2025-06-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001803
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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001803

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