Ferroptosis in neurodegenerative diseases: mechanisms and therapeutic potential of stem cell derivatives

Ferroptosis in neurodegenerative diseases: mechanisms and therapeutic potential of stem cell derivatives

Ferroptosis, a non-apoptotic, iron-dependent form of regulated cell death, is closely related to the pathogenesis of neurodegenerative diseases. Stem cells and their derivatives exhibit remarkable potential in modulating ferroptosis, offering promising therapeutic intervention for neurodegenerative...

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Main Authors: Ting Zhang, Yusu Zhang, Jinpeng Xie, Dandan Lu, Lihong Wang, Shuaifei Zhao, Jing Zhou, Yang Cheng, Ting Kou, Jue Wang, Ying Chen, Lei Xu, Xiangyu Hu, Yuxiu Ying, Jun Wang, Xiaoshuang Xin, Xu Xu, Siyun Lei, Chenyu Qiu, Jinhua Wu, Qiqi Lyu, Tong Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ferroptosis
neurodegenerative diseases
aging
stem cell derivatives
neuroprotection
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1577382/full
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https://www.frontiersin.org/articles/10.3389/fcell.2025.1577382/full

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