DISCOVERY OF NOVEL EPIGENETIC BIOMARKERS IN ORAL MALIGNANT LESIONS BY EPIGENOMICS AND TRANSCRIPTOMICS APPROACHES

DISCOVERY OF NOVEL EPIGENETIC BIOMARKERS IN ORAL MALIGNANT LESIONS BY EPIGENOMICS AND TRANSCRIPTOMICS APPROACHES

Objectives: DNA methylation, which is the most frequently observed epigenetic change, is very important because it is seen in the early stages of cancer. Abnormal methylation of promoter regions and silencing of tumor suppressor genes play a key role in the development of oral squamous cell carcinom...

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Main Authors: Semra Demokan, Sena Şen, Begüm Özemek, Sevde Cömert, Önder Eryılmaz, Murat Ulusan, Necati Enver, Uğur Sezerman, Gülsüm Ak, F. Canan Alatlı, Mehmet Nejat Dalay
Format: Article
Language:English
Published: Istanbul University Press 2022-08-01
Series:Sabiad
Subjects:
epigenomics
transcriptomics
oscc
biomarker
non-invasive
Online Access:https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/FC758443577140F88914D5091C650D39
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https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/FC758443577140F88914D5091C650D39

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