Comparative analysis of melatonin’s protective role against flattening filter and flattening filter-free X-ray induced nephropathy: focus on apoptosis and SIRT1 modulation
Abstract Background Radiation-induced nephropathy is a major concern, particularly for patients undergoing radiotherapy. This study investigates melatonin’s (MEL) protective effects against kidney damage induced by Flattening Filter (low dose rate-LDR) and Flattening Filter Free (high dose rate-HDR)...
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| Main Authors: | Kubra Sevgin, Tansel Sapmaz, Esra Erdem, Sude Topkaraoglu, Kubra Basol Baki, Serhat Aras |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Nephrology |
| Online Access: | https://doi.org/10.1186/s12882-025-04372-0 |
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