Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

Tissue engineering strategies predominantly rely on the production of living substitutes, whereby implanted cells actively participate in the regenerative process. Beyond cost and delayed graft availability, the patient-specific performance of engineered tissues poses serious concerns on their clini...

Full description

Saved in:
Bibliographic Details
Main Authors: Sujeethkumar Prithiviraj, Alejandro Garcia Garcia, Karin Linderfalk, Bai Yiguang, Sonia Ferveur, Ludvig Nilsén Falck, Agatheeswaran Subramaniam, Sofie Mohlin, David Hidalgo Gil, Steven J Dupard, Dimitra Zacharaki, Deepak Bushan Raina, Paul E Bourgine
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
extracellular matrix
bone marrow mesenchymal stem cells
bone marrow mesenchymal stromal cells
tissue engineering
bone
cartilage
Online Access:https://elifesciences.org/articles/96941
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://elifesciences.org/articles/96941

Similar Items