Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress

Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress

Abstract Hypoxia is increasingly recognized as an important physiological driving force. A specific transcriptional program, induced by a decrease in oxygen (O2) availability, for example, inspiratory hypoxia at high altitude, allows cells to adapt to lower O2 and limited energy metabolism. This tra...

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Bibliographic Details
Main Authors: Hannelore Ehrenreich, Max Gassmann, Luise Poustka, Martin Burtscher, Peter Hammermann, Anna‐Leena Sirén, Klaus‐Armin Nave, Kamilla Miskowiak
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Neuroprotection
Subjects:
brain EPO circle
erythropoietin
functional hypoxia
HIF
human pilot study
hyperoxia
Online Access:https://doi.org/10.1002/nep3.15
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https://doi.org/10.1002/nep3.15

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