Attenuation of PM2.5-Induced Lung Injury by 4-Phenylbutyric Acid: Maintenance of [Ca<sup>2+</sup>]i Stability between Endoplasmic Reticulum and Mitochondria

Attenuation of PM2.5-Induced Lung Injury by 4-Phenylbutyric Acid: Maintenance of [Ca<sup>2+</sup>]i Stability between Endoplasmic Reticulum and Mitochondria

Fine particulate matter (PM2.5) is a significant cause of respiratory diseases and associated cellular damage. The mechanisms behind this damage have not been fully explained. This study investigated two types of cellular damage (inflammation and pyroptosis) induced by PM2.5, focusing on their relat...

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Bibliographic Details
Main Authors: Zhenhua Ma, Xiaohui Du, Yize Sun, Yunna Jia, Xiaojun Liang, Yunhang Gao
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Biomolecules
Subjects:
PM2.5
4-PBA
intracellular Ca<sup>2+</sup>
ER stress
mitochondrial damage
pyroptosis
Online Access:https://www.mdpi.com/2218-273X/14/9/1135
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