The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics

The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal te...

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Main Authors: Christina Fellinger, Felix Wantke, Wolfgang Hemmer, Gabriele Sesztak-Greinecker, Stefan Wöhrl
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/201586
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author Christina Fellinger
Felix Wantke
Wolfgang Hemmer
Gabriele Sesztak-Greinecker
Stefan Wöhrl
author_facet Christina Fellinger
Felix Wantke
Wolfgang Hemmer
Gabriele Sesztak-Greinecker
Stefan Wöhrl
author_sort Christina Fellinger
collection DOAJ
description The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal testing were done with lidocaine, mepivacaine, and procaine. Intradermal testing showed positive reactions to mepivacaine (1 : 10), undiluted lidocaine, and procaine (1 : 10 and undiluted). Specific IgE could be detected against mepivacaine, but not against latex. Serum tryptase was in the normal range. In order to rule out the exceptional case of a true IgE-mediated reaction, allergy testing with local anaesthetics is still required in the workup of patients.
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institution Kabale University
issn 1687-9627
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publishDate 2013-01-01
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series Case Reports in Medicine
spelling doaj-art-18cd2e1b486f4be18f656b1e46889e212025-02-03T01:32:40ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/201586201586The Rare Case of a Probably True IgE-Mediated Allergy to Local AnaestheticsChristina Fellinger0Felix Wantke1Wolfgang Hemmer2Gabriele Sesztak-Greinecker3Stefan Wöhrl4Floridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8/6, 1210 Vienna, AustriaFloridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8/6, 1210 Vienna, AustriaFloridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8/6, 1210 Vienna, AustriaFloridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8/6, 1210 Vienna, AustriaFloridsdorf Allergy Centre (FAZ), Franz Jonas Platz 8/6, 1210 Vienna, AustriaThe majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal testing were done with lidocaine, mepivacaine, and procaine. Intradermal testing showed positive reactions to mepivacaine (1 : 10), undiluted lidocaine, and procaine (1 : 10 and undiluted). Specific IgE could be detected against mepivacaine, but not against latex. Serum tryptase was in the normal range. In order to rule out the exceptional case of a true IgE-mediated reaction, allergy testing with local anaesthetics is still required in the workup of patients.http://dx.doi.org/10.1155/2013/201586
spellingShingle Christina Fellinger
Felix Wantke
Wolfgang Hemmer
Gabriele Sesztak-Greinecker
Stefan Wöhrl
The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
Case Reports in Medicine
title The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_full The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_fullStr The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_full_unstemmed The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_short The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_sort rare case of a probably true ige mediated allergy to local anaesthetics
url http://dx.doi.org/10.1155/2013/201586
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