Overexpression of OTX2 in human neural cells links depression risk genes
Abstract Genome wide association studies (GWAS) have implicated the OTX2 (Orthodenticle homeobox 2) gene locus in major depressive disorders (MDD) as well as genetically correlated traits. Of the genes identified by MDD GWAS, the gene for the transcription factor OTX2 stands out as it is responsible...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-04-01
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| Series: | Translational Psychiatry |
| Online Access: | https://doi.org/10.1038/s41398-025-03320-8 |
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