Identification of CaVβ1 Isoforms Required for Neuromuscular Junction Formation and Maintenance

Identification of CaVβ1 Isoforms Required for Neuromuscular Junction Formation and Maintenance

Voltage-gated Ca<sup>2+</sup> channels (VGCCs) are regulated by four CaVβ subunits (CaVβ1–CaVβ4), each showing specific expression patterns in excitable cells. While primarily known for regulating VGCC function, CaVβ proteins also have channel-independent roles, including gene expression...

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Main Authors: Amélie Vergnol, Aly Bourguiba, Stephanie Bauché, Massiré Traoré, Maxime Gelin, Christel Gentil, Sonia Pezet, Lucile Saillard, Pierre Meunier, Mégane Lemaitre, Julianne Perronnet, Frederic Tores, Candice Gautier, Zoheir Guesmia, Eric Allemand, Eric Batsché, France Pietri-Rouxel, Sestina Falcone
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Cells
Subjects:
CaVβ isoforms
neuromuscular junctions
skeletal muscle
Cacnb1
promoters
Long-read sequencing
Online Access:https://www.mdpi.com/2073-4409/14/15/1210
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