Supervised fine-tuning of pre-trained antibody language models improves antigen specificity prediction.

Antibodies play a crucial role in the adaptive immune response, with their specificity to antigens being a fundamental determinant of immune function. Accurate prediction of antibody-antigen specificity is vital for understanding immune responses, guiding vaccine design, and developing antibody-base...

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Bibliographic Details
Main Authors: Meng Wang, Jonathan Patsenker, Henry Li, Yuval Kluger, Steven H Kleinstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012153
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