Considerations for homology-based DNA repair in mosquitoes: Impact of sequence heterology and donor template source.
The increasing prevalence of insecticide resistance and the ongoing global burden of vector-borne diseases have encouraged new efforts in mosquito control. For Aedes aegypti, the most important arboviral vector, integration rates achieved in Cas9-based knock-ins so far have been rather low, highligh...
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| Main Authors: | Joshua Xin De Ang, Katherine Nevard, Rebekah Ireland, Deepak-Kumar Purusothaman, Sebald A N Verkuijl, Lewis Shackleford, Estela Gonzalez, Michelle A E Anderson, Luke Alphey |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-02-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010060&type=printable |
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