Elevated serum levels of interleukin-18 discriminate Still’s disease from other autoinflammatory conditions: results from the European ImmunAID cohort

Elevated serum levels of interleukin-18 discriminate Still’s disease from other autoinflammatory conditions: results from the European ImmunAID cohort

Objectives Systemic autoinflammatory diseases (SAIDs) represent a set of conditions with exaggerated innate immune responses. IL-1β and IL-18 are key cytokines involved in the pathogenesis of some SAID. We aimed to assess the diagnostic value of serum levels of IL-1β, IL-18, their respective inhibit...

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Main Authors: Bruno Fautrel, David Saadoun, Tadej Avcin, Thierry Martin, Eric Hachulla, Cem Gabay, Seza Ozen, Stéphanie Humblet-Baron, Carine Wouters, Adrian Liston, Umut Kalyoncu, Jordi Antón, Sinisa Savic, Yvan Jamilloux, Christoph Kessel, Dirk Foell, Jeroen Raes, Michael Hofer, Luca Cantarini, Isabelle Kone-Paut, Søren Brunak, Marie-Elise Truchetet, Steven Vanderschueren, Alexandre Belot, Antonella Insalaco, Haner Direskeneli, Irina Giurgea, Sophie Georgin-Lavialle, Serge Amselem, Léa Savey, Pierre Quartier, Anne Boland, Jean-François Deleuze, Sabrina Carpentier, Katerina Laskari, Thomas Henry, Jean-David Bouaziz, Clementien Vermont, Emanuele Bizzi, Helen Lachmann, Nicolas Poursac, Gilles Hayem, Stéphane Mitrovic, Patrick Matthys, Isabella Friis Jørgensen, Emiliana Rodriguez, Philippe Hupé, Paolo Sfriso, Evangelos Andreakos, Antoine Néel, Alina Boteanu, Sara Garcia, Perrine Dusser, Yvonne M Mueller, Peter D Katsikis, Matheus Vieira, Charlotte Girard-Guyonvarc’h, Charlotte Girard, Assunta Caruso, Violeta Bittermann, Sonia Caccia, Arturo Hernandez Cervantes, Emna Chabaane, Fanny Coffin, Dominique de Seny, Henri de Soyres, Marc Dubourdeau, Stefan J Erkeland, Dimitrios I. Fotiadis, Apolline Gallois, Mieke Gouwy, Sonia Karabina, Andres Jimenez Kaufmann, Keshia Koutekissa, Karoline Krause, Thibault Mahevas, Nasima Matsa, Michael F. McDermott, Aura Moreno Vega, Marco Francesco Natale, Maria Papadaki, Costas Papaloukas, Christophe Poulet, Sebastian Proost, Paul Proost, Julien Roméjon, Sarhan Yaiche, Savvas Savvides, Vassili Soumelis, Sigrid Swagemakers, Paul Van Daele, Harmen J. G. vandeWerken, Peter van derSpek, Rogier van Wijck
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/2/e005388.full
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