The expression of fungal CotH, human glucose-regulated protein 78 (GRP78), and predicted miRNAs in macrophages and diabetic mice infected with Rhizopus oryzae

The expression of fungal CotH, human glucose-regulated protein 78 (GRP78), and predicted miRNAs in macrophages and diabetic mice infected with Rhizopus oryzae

ABSTRACT The spore coat protein homolog (CotH) has been identified among virulence factors of Mucorales that mediate fungal invasion by glucose-regulated protein 78 (GRP78) ligand on endothelial cells. The aim of this study was to examine the gene expressions of spore coat protein homolog 3 (CotH3)...

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Main Authors: Zahra Seifi, Tahereh Shokohi, Mohammad Shafiee, Seyed Javad Mowla, Farhad Niknejad, Emmanuel Edwar Siddig, Ayman Ahmed, Mahdi Abastabar, Laleh Vahedi Larijani
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
mucormycosis
Rhizopus oryzae
macrophages
diabetic mice
CotH protein
miRNAs
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02852-24
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https://journals.asm.org/doi/10.1128/spectrum.02852-24

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