Calcium oscillations in mesenchymal stem cells, a control on cell cycle progression to influence cell fate towards proliferation or differentiation?

Calcium oscillations in mesenchymal stem cells, a control on cell cycle progression to influence cell fate towards proliferation or differentiation?

Abstract Background Under regular culture conditions, mesenchymal stem cells (MSCs) exhibit cytosolic calcium concentration oscillations (Ca2+ oscillations), that change, especially in frequency, after the differentiation of the MSCs. Ca2+ oscillations are known to encode important information in fr...

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Main Authors: Leslie A. Vallet, Marina Sánchez-Petidier, Romain Fernandes, Nataliia Naumova, Caterina Merla, Claudia Consales, Giorgia Innamorati, Franck M. André, Lluis M. Mir
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Subjects:
Cell proliferation
Electrical stimulation
Cell cycle control
Microsecond pulsed electric fields
Electroporation
Electropermeabilization
Online Access:https://doi.org/10.1186/s13287-025-04454-8
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https://doi.org/10.1186/s13287-025-04454-8

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