Stereochemistry of the Carbon-Nitrogen Bond Cleavage by Chloroformate Esters

Nicotine reacts with chloroformic esters to give the chloro-carbamates resulting from the cleavage of the C2' –N1' bond. The reaction is shown to proceed with at least 96 to 98 % inversion of configuration. In the same way, (R)-(+)-N,N-dimethyl-α-phenethylamine gave (S)-(−)-α-phenethyl ch...

Full description

Saved in:
Bibliographic Details
Main Authors: C. Hootelé, J.P. Lenders
Format: Article
Language:deu
Published: Swiss Chemical Society 1974-11-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9188
Tags: Add Tag
No Tags, Be the first to tag this record!