Effects of Testosterone and Its Major Metabolites upon Different Stages of Neuron Survival in the Dentate Gyrus of Male Rats

Effects of Testosterone and Its Major Metabolites upon Different Stages of Neuron Survival in the Dentate Gyrus of Male Rats

Testosterone has been shown to enhance hippocampal neurogenesis through increased cell survival, but which stages of new neuron development are influenced by testosterone remains unclear. Therefore, we tested the effects of sex steroids administered during three different periods after cell division...

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Bibliographic Details
Main Authors: Mark D. Spritzer, Ethan A. Roy, Kelsey M. K. Calhoun, Zachary E. Schneider-Lynch, Leslie Panella, Charlotte Michaelcheck, April Qian, Evan D. Kelly, Hadley Barr, Emma Hall, Blaine Cunningham, Hieu H. M. Nguyen, Dani Xu, Jennifer M. Barker, Liisa A. M. Galea
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomolecules
Subjects:
adult neurogenesis
cell proliferation
dentate gyrus
hippocampus
testosterone
estradiol
Online Access:https://www.mdpi.com/2218-273X/15/4/542
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