Molecular evolution and functional characterization of Drosophila insulin-like peptides.

Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway plays key roles in growth, metabolism, stress resistance, reproduction, and longevity in diverse organisms including mammals....

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Bibliographic Details
Main Authors: Sebastian Grönke, David-Francis Clarke, Susan Broughton, T Daniel Andrews, Linda Partridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000857&type=printable
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