Aspirin Resistance

The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical e...

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Main Authors: Khaled Mansour, Ali T. Taher, Khaled M. Musallam, Samir Alam
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2009/937352
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author Khaled Mansour
Ali T. Taher
Khaled M. Musallam
Samir Alam
author_facet Khaled Mansour
Ali T. Taher
Khaled M. Musallam
Samir Alam
author_sort Khaled Mansour
collection DOAJ
description The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety.
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institution Kabale University
issn 1687-9104
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language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series Advances in Hematology
spelling doaj-art-17da7af7c1194abbb7d9a7a1a29f64142025-02-03T01:26:49ZengWileyAdvances in Hematology1687-91041687-91122009-01-01200910.1155/2009/937352937352Aspirin ResistanceKhaled Mansour0Ali T. Taher1Khaled M. Musallam2Samir Alam3Division of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonDivision of Hematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonDivision of Hematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonDivision of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonThe development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety.http://dx.doi.org/10.1155/2009/937352
spellingShingle Khaled Mansour
Ali T. Taher
Khaled M. Musallam
Samir Alam
Aspirin Resistance
Advances in Hematology
title Aspirin Resistance
title_full Aspirin Resistance
title_fullStr Aspirin Resistance
title_full_unstemmed Aspirin Resistance
title_short Aspirin Resistance
title_sort aspirin resistance
url http://dx.doi.org/10.1155/2009/937352
work_keys_str_mv AT khaledmansour aspirinresistance
AT alittaher aspirinresistance
AT khaledmmusallam aspirinresistance
AT samiralam aspirinresistance