Aspirin Resistance
The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical e...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2009-01-01
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Series: | Advances in Hematology |
Online Access: | http://dx.doi.org/10.1155/2009/937352 |
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author | Khaled Mansour Ali T. Taher Khaled M. Musallam Samir Alam |
author_facet | Khaled Mansour Ali T. Taher Khaled M. Musallam Samir Alam |
author_sort | Khaled Mansour |
collection | DOAJ |
description | The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety. |
format | Article |
id | doaj-art-17da7af7c1194abbb7d9a7a1a29f6414 |
institution | Kabale University |
issn | 1687-9104 1687-9112 |
language | English |
publishDate | 2009-01-01 |
publisher | Wiley |
record_format | Article |
series | Advances in Hematology |
spelling | doaj-art-17da7af7c1194abbb7d9a7a1a29f64142025-02-03T01:26:49ZengWileyAdvances in Hematology1687-91041687-91122009-01-01200910.1155/2009/937352937352Aspirin ResistanceKhaled Mansour0Ali T. Taher1Khaled M. Musallam2Samir Alam3Division of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonDivision of Hematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonDivision of Hematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonDivision of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut 1107 2020, LebanonThe development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety.http://dx.doi.org/10.1155/2009/937352 |
spellingShingle | Khaled Mansour Ali T. Taher Khaled M. Musallam Samir Alam Aspirin Resistance Advances in Hematology |
title | Aspirin Resistance |
title_full | Aspirin Resistance |
title_fullStr | Aspirin Resistance |
title_full_unstemmed | Aspirin Resistance |
title_short | Aspirin Resistance |
title_sort | aspirin resistance |
url | http://dx.doi.org/10.1155/2009/937352 |
work_keys_str_mv | AT khaledmansour aspirinresistance AT alittaher aspirinresistance AT khaledmmusallam aspirinresistance AT samiralam aspirinresistance |