SPAG5 is a potential therapeutic target affecting proliferation, apoptosis, and invasion of esophageal cancer cells

Abstract Background Sperm-associated antigen 5 (SPAG5) is a mitotic spindle protein crucial for coordinating the separation of sister chromatids into daughter cells. Increasing evidence suggests that SPAG5 is overexpressed in various malignancies, functioning as an oncogene. However, research specif...

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Bibliographic Details
Main Authors: Xiaohui Zhang, Lingmin Zhang, Manli Cui, Shiyu Ji, Yanan Zhang, Qian Li, Mingxin Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-024-02182-y
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