Manipulation of the Complement System for Benefit in Sepsis
There is evidence in sepsis, both in rodents and in humans, that activation of the complement system results in excessive production of C5a, which triggers a series of events leading to septic shock, multiorgan failure, and lethality. In rodents following cecal ligation and puncture (CLP), which in...
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Main Authors: | Peter A. Ward, Ren-Feng Guo, Niels C. Riedemann |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Critical Care Research and Practice |
Online Access: | http://dx.doi.org/10.1155/2012/427607 |
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