Mutational Insights into GyrA and GyrB Genes in Mycobacterium tuberculosis: A Genetic Basis for Fluoroquinolone Resistance in Multidrug-resistant Tuberculosis

Mutational Insights into GyrA and GyrB Genes in Mycobacterium tuberculosis: A Genetic Basis for Fluoroquinolone Resistance in Multidrug-resistant Tuberculosis

The global tuberculosis (TB) epidemic is becoming progressively more complex due to the increasing prevalence of multidrug-resistant TB (MDR-TB), particularly with resistance to fluoroquinolones (FQs). This study focuses on identifying genetic mutations in the gyrA and gyrB genes of Mycobacterium tu...

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Bibliographic Details
Main Authors: Anam Shafiq, Haris Manzoor Khan, Mohd. Shahid, Nazish Fatima, Mo Ahamad Khan
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2024-12-01
Series:Journal of Pure and Applied Microbiology
Subjects:
mdr-tb
fluoroquinolone resistance
gyra mutations
gyrb mutations
diagnosis
sequence analysis
Online Access:https://microbiologyjournal.org/mutational-insights-into-gyra-and-gyrb-genes-in-mycobacterium-tuberculosis-a-genetic-basis-for-fluoroquinolone-resistance-in-multidrug-resistant-tuberculosis/
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https://microbiologyjournal.org/mutational-insights-into-gyra-and-gyrb-genes-in-mycobacterium-tuberculosis-a-genetic-basis-for-fluoroquinolone-resistance-in-multidrug-resistant-tuberculosis/

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