Bardoxolone methyl suppressed colorectal cancer cells in vitro by inhibiting the PI3K signaling pathway

Abstract The occurrence and death rates of colorectal cancer (CRC) have been consistently increasing, demanding the immediate requirement for the creation of dependable and effective medicinal treatments. This study investigates bardoxolone methyl (CDDO-Me), a synthetic triterpenoid, as a potential...

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Bibliographic Details
Main Authors: Linlin Zhang, Qiaoling Huang, Jingqing Yang, Ye Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-00480-x
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