Synthesis and evaluation of quinolinvinyl-phenoxy-1,2,3-triazole-acetamide hybrids against breast cancer

Synthesis and evaluation of quinolinvinyl-phenoxy-1,2,3-triazole-acetamide hybrids against breast cancer

Abstract This work synthesized and evaluated a new series of quinolinvinyl-phenoxy-1,2,3-triazole-acetamide hybrids 9a-p against breast cancer cell lines, including MCF-7 and MDA-MB-231. Among 16 synthesized compounds, (E)-N-(4-chlorophenyl)-2-(4-((4-(2-(quinolin-2-yl)vinyl)phenoxy)methyl)-1H-1,2,3-...

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Bibliographic Details
Main Authors: Maliheh Safavi, Aida Iraji, Sara Moghadam Farid, Mohammad Mahdavi, Samaneh Fattaheian-Dehkordi, Tahmineh Akbarzadeh, Mina Saeedi
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Anti-cancer
Apoptosis
Quinolinvinyl
1,2,3-triazole
Online Access:https://doi.org/10.1038/s41598-025-01051-w
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https://doi.org/10.1038/s41598-025-01051-w

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