In silico docking of forchlorfenuron (FCF) to septins suggests that FCF interferes with GTP binding.

Septins are GTP-binding proteins that form cytoskeleton-like filaments, which are essential for many functions in eukaryotic organisms. Small molecule compounds that disrupt septin filament assembly are valuable tools for dissecting septin functions with high temporal control. To date, forchlorfenur...

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Bibliographic Details
Main Authors: Dimitrios Angelis, Eva Pauline Karasmanis, Xiaobo Bai, Elias T Spiliotis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096390&type=printable
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