Advancements and challenges in personalized neoantigen-based cancer vaccines

Advancements and challenges in personalized neoantigen-based cancer vaccines

Advancements in personalized neoantigen-based cancer vaccines are ushering in a new era in oncology, targeting unique genetic alterations within tumors to enhance treatment precision and efficacy. Neoantigens, specific to cancer cells and absent in normal tissues, are at the heart of these vaccines,...

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Main Authors: Parminder Singh, Mahalaqua Nazli Khatib, Roopashree R, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Rajput, Pranchal Rajput, Rukshar Syed, Gajendra Sharma, Sunil Kumar, Muhammed Shabil, Sakshi Pandey, Manvinder Brar, Ganesh Bushi, Rachana Mehta, Sanjit Sah, Khang Wen Goh, Prakasini Satapathy, Abhay M. Gaidhane, Shailesh Kumar Samal
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Oncology Reviews
Subjects:
neoantigen-based vaccines
cancer immunotherapy
personalized medicine
vaccine delivery systems
immunogenicity prediction
Online Access:https://www.frontiersin.org/articles/10.3389/or.2025.1541326/full
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https://www.frontiersin.org/articles/10.3389/or.2025.1541326/full

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