Fc fragment of IgG binding protein suppresses tumor growth by stabilizing wild type P53 in colorectal cancer cells

Fc fragment of IgG binding protein suppresses tumor growth by stabilizing wild type P53 in colorectal cancer cells

Abstract The Fc fragment of IgG binding protein (FCGBP) exhibits differential expression across various tumor types. but its role in cancer progression remains underexplored. This research discovered that FCGBP is downregulated in colorectal cancer (CRC) cells and is negatively associated with poor...

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Bibliographic Details
Main Authors: Jiefu Wang, Ziqing Gong, Jia Liu, Wenpeng Wang, Kai Liu, Yanpeng Yang, Xinran Lu, Junfeng Wang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
Subjects:
Fc fragment of IgG binding protein
Colorectal cancer
Wild type P53
Ubiquitination
MDM2
Online Access:https://doi.org/10.1186/s12885-025-13873-y
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https://doi.org/10.1186/s12885-025-13873-y

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