Optimization of Extraction Parameters of Phenolic Compounds from Cau Banana (Musa paradisiaca) Peel and Evaluation for Antioxidant and Antibacterial Potential
Objective: This study aims to demonstrate the potential reuse of Cau banana peel (CBP), a fruit by-product in the Mekong Delta, Vietnam, based on its antioxidant and antibacterial activity. Materials and Methods: The determination of optimal extraction conditions for phenolics using response surface...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Istanbul University Press
2024-12-01
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| Series: | European Journal of Biology |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/D9ED7AD55486495AABD214D91A34C72B |
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| Summary: | Objective: This study aims to demonstrate the potential reuse of Cau banana peel (CBP), a fruit by-product in the Mekong Delta, Vietnam, based on its antioxidant and antibacterial activity. Materials and Methods: The determination of optimal extraction conditions for phenolics using response surface methodology from CBP powder. Then, the CBP extract was evaluated for total phenolic content (TPC), flavonoid content (TFC), phytochemical constituents, and antioxidant activity by the DPPH free radical scavenging assay, whereas antibacterial effects against the pathogens Staphylococcus aureus and Escherichia coli were determined by the agar diffusion and broth dilution methods. Results: The highest TPC (38.42 mgGAE/g) and TFC (9.75 mgQE/g) were achieved with 1 g of the CBP powder, 58 mL of 60% ethanol solution, and 76 min of processing time at 56°C. The CBP extract contained tannins, flavonoids, alkaloids, saponins, and glycosides, with TPC and TFC of 543.48 mgGAE/g and 158.96 mgQE/g, respectively. The IC50 was 105.85 μg/mL, and the MBC/MIC ratios were ≤2.0 mg/mL. Therefore, it could be a strong antioxidant and bactericidal agent. Conclusion: These results show that the peel waste of CBP could be helpful in the medical or health food industry for various applications instead of dumping them in landfills. |
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| ISSN: | 2618-6144 |