Exploring a tristhione scorpionate ligand as a suitable chelator for the theranostic pair antimony-119 and antimony-117

Exploring a tristhione scorpionate ligand as a suitable chelator for the theranostic pair antimony-119 and antimony-117

Abstract Background The highly potent Auger electron emitter antimony-119 (119Sb) and the SPECT-isotope antimony-117 (117Sb) comprise a true theranostic pair particularly suitable for cancer theranostics. Harnessing this potential requires development of a chelator that can rapidly form a stable com...

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Main Authors: Lorraine Gaenaelle Gé, Mads Sondrup Møller, Catherine Chen, Virginia Cendán Castillo, Niels Langkjaer, Vickie McKee, Johan Hygum Dam, Christine J. McKenzie, Helge Thisgaard
Format: Article
Language:English
Published: SpringerOpen 2024-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Antimony
119Sb
117Sb
Scorpionate ligand
Theranostic pair
Radiolabelling
Online Access:https://doi.org/10.1186/s41181-024-00297-5
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https://doi.org/10.1186/s41181-024-00297-5

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