Development of a prognostic immune cell-based model for ovarian cancer using multiplex immunofluorescence

Development of a prognostic immune cell-based model for ovarian cancer using multiplex immunofluorescence

Abstract Background Ovarian cancer is the most lethal gynecological malignancy, often diagnosed at advanced stages with poor prognosis. The tumor microenvironment (TME) plays a critical role in disease progression and treatment response. This study aimed to construct a prognostic model for ovarian c...

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Bibliographic Details
Main Authors: Sai Li, Boyang Jiang, Hongying Zhou, Sifu Yang, Liu Yang, Yupeng Hong
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Ovarian cancer
Multiplex immunofluorescence (mIF)
Spatial analysis
Immune Cell Related Prognostic Index (ICRPI) model
Nomogram
Online Access:https://doi.org/10.1186/s12967-025-06745-3
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https://doi.org/10.1186/s12967-025-06745-3

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