Induction of TLR5, IRAK1, and NF-κB expression by Trichomonas vaginalis in cervical cancer cell (HeLa) and normal human vaginal epithelial cell (HVECs) lines

Induction of TLR5, IRAK1, and NF-κB expression by Trichomonas vaginalis in cervical cancer cell (HeLa) and normal human vaginal epithelial cell (HVECs) lines

Introduction: Trichomoniasis is the most common non-viral sexually transmitted infection that increases the risk of cervical cancer. Trichomonas vaginalis (T. vaginalis) can regulate the pro-inflammatory cytokine production in the host cells. Toll-like receptors (TLRs) are a family of the pattern r...

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Main Authors: Soraya Mohammadi Esfanjani, Leili Aghebati Maleki, Sanam Nami, Mina Ebrahimi, Amir Baghbanzadeh, Gregorio Perez-Cordon, Sonia M Rodrigues Oliveira, Maria de Lourdes Pereira, Aleksandra Barać, Ehsan Ahmadpour, Jelena Micić
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2023-08-01
Series:Journal of Infection in Developing Countries
Subjects:
Human vaginal epithelial cell
inflammation
in vitro
TLR5
trichomoniasis
Online Access:https://jidc.org/index.php/journal/article/view/18066
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https://jidc.org/index.php/journal/article/view/18066

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