Correlation of rivaroxaban solubility in mixed solvents for optimization of solubility using machine learning analysis and validation
Abstract In this study, the solubility of rivaroxaban, a poorly water-soluble drug, was investigated in mixed solvent systems to address challenges in pharmaceutical formulation and bioavailability enhancement. Solubility optimization is essential for the effective delivery and therapeutic performan...
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Main Authors: | Muteb Alanazi, Jowaher Alanazi, Tareq Nafea Alharby, Bader Huwaimel |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-89093-y |
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