Correlation of rivaroxaban solubility in mixed solvents for optimization of solubility using machine learning analysis and validation

Abstract In this study, the solubility of rivaroxaban, a poorly water-soluble drug, was investigated in mixed solvent systems to address challenges in pharmaceutical formulation and bioavailability enhancement. Solubility optimization is essential for the effective delivery and therapeutic performan...

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Bibliographic Details
Main Authors: Muteb Alanazi, Jowaher Alanazi, Tareq Nafea Alharby, Bader Huwaimel
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-89093-y
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