Baicalin alleviates sepsis-associated acute kidney injury through activation of the PPAR-γ/UCP1 signaling pathway

Baicalin alleviates sepsis-associated acute kidney injury through activation of the PPAR-γ/UCP1 signaling pathway

Purpose This study aims to investigate the protective effect of baicalin on sepsis-associated acute kidney injury (SA-AKI) and its molecular mechanism.Materials and methods An SA-AKI mouse model was established via lipopolysaccharide (LPS) injection. Baicalin’s effects on renal function, oxidative s...

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Bibliographic Details
Main Authors: Neng Bao, Ming-Jia Gu, Qiu-Ya Huang, Hai-Jian Sun, Xue-Xue Zhu, Xin Gu, Jin Wang, Xiang Yu, Qing-Bo Lu, Ya-Fen Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Baicalin
sepsis
acute kidney injury
mitochondrion
UCP1
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2508908
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2508908

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